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Dr. Efrati has initiated a research program focusing on the neuroplasticity (regeneration of brain tissue) of Hyperbaric Oxygen Therapy (HBOT). In the first clinical studies it was proved that HBOT can induce neuroplasticity in post stroke and Traumatic Brain Injury even years after the acute Insult. The important clinical results gained from the research program have led to fruitful cooperation including multidiscipline team focusing on regeneration of injured brain due to early stages of dementia, vascular disease and anoxic brain damage as well as other "aging" tissues.